IntroductionLeprosy is an infectious disease that remains with a high number of new cases in developing countries.Household contacts have a higher risk for the development of the disease, but the neural impairment in this group is not well elucidated yet.Here, we measured the chance of occurrence of peripheral neural impairment in asymptomatic lepr
The impact of sugarcane production on biodiversity related to land use change in Ethiopia
Ethiopia produces sugar and ethanol from sugarcane as an integrated business.Ethanol production is expected to increase from 30,000 to over 300,000 metric tonnes per year R-Alpha Lipoic Acid in the second growth and transformation plan (GTP II) of 2020.In GTP II, the total sugarcane plantation area will be 320,000 ha.The intense acquisition of land
Protocol: Improving Access to Specialist Nephrology Care Among Rural/Remote Dwellers of Alberta: The Role of Electronic Consultation in Improving Care for Patients With Chronic Kidney Disease
Background: As the burden of chronic kidney disease (CKD) continues to increase, many geographically dispersed Canadians have limited access to specialist nephrology care, which tends to be centralized in major urban areas.As a result, many rural/remote-dwellers in Canada experience poor quality of care and related adverse outcomes.It is imperative
Autocatalytic base editing for RNA-responsive translational control
Genetic circuits that control transgene expression in response to pre-defined transcriptional Phased Array TV Antenna cues would enable the development of smart therapeutics.Here the authors engineer programmable RNA sensors, DART VADARs, in which ADARs Lid Switch autocatalytically convert target hybridization into a translational output, thus ampl
The impact of comorbid psychiatric disorders on methadone maintenance treatment in opioid use disorder: a prospective cohort study
Tea Rosic,1 Leen Naji,2 Monica Bawor,3 Brittany B Dennis,3 Carolyn Plater,4 David C Marsh,5 Lehana Thabane,6–8 Zainab Samaan6–11 1St Joseph’s Healthcare, 2Michael G DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada; 3St George’s University of London, London, UK; 4Canadian Addiction Treatment Centre, Rich